Analysis of characteristics of non-contact automatic ultrasonic cell disruption instrument

Shanghai Xinzhuang Instrument Co., Ltd. adheres to the leading business philosophy of technological innovation and technology, and continues to make new contributions to the development of human social undertakings by carrying out strategic innovations and innovative product innovations. It is a company that integrates R&D, production and sales. Excellent product quality, excellent service, the company specializes in producing all kinds of laboratory equipment.
Characteristics of non-contact automatic ultrasonic cell disruption instrument The non-contact automatic ultrasonic cell disruption instrument can obtain the unparalleled quality, efficiency and safety of traditional ultrasonic methods. This innovation has been widely used in Europe and the United States and has gradually become an indispensable standardized tool for the ChIP (Chromatin Immunoprecipitation) research platform.

The traditional probe ultrasonic crusher, the probe is in direct contact with the sample, can only process one sample at a time, and the test period is long; for multiple samples, the same probe needs to be reused, which is easy to cause cross-contamination of the sample. Because the depth of each probe inserted into the sample is different, the energy distribution of each ultrasound is also different, which affects the repeatability and accuracy of the experimental results. In addition, because a closed system cannot be used, the aerosol or foam generated during the ultrasound process can spread into the environment, posing a potential biological hazard.

Non-contact automatic ultrasonic crusher, which can detect 6 to 12 samples at the same time, with high efficiency; no need to operate the probe frequently, each sample is in a separate fully enclosed test tube to avoid cross-contamination; use 4 °C water bath ultrasonic, energy The distribution is uniform, the ultrasonic effect is complete; the ultrasonic parameters are flexible, the experimental steps are standardized, the experimental repeatability is good, and the results are highly reliable.

Ingenious working principle: the design of the ultrasonic generating device installed at the bottom of the sink. The traditional probe ultrasonic shattering instrument, the micro-flow phenomenon caused by the ultrasonic wave can only appear in the area close to the probe, and the ultrasonic cell crusher is installed by the ultrasonic wave at the bottom of the water tank. The water is completely in the range of the ultrasonic wave, and the ultrasonic action is widely distributed and balanced, which reduces the formation of foam. During the experiment, the ultrasonic cell crusher automatically rotates the centrifuge tube continuously to make the ultrasonic energy distribution more uniform.

During the experiment, the samples were placed in separate fully sealed centrifuge tubes, and there was no cross-contamination between the samples, which avoided the propagation of aerosols and enhanced the biosafety of the experiments. For larger systems with 15 ml centrifuge tubes, the ultrasonic cell disruptor also features a patented resonance system that conducts ultrasonic waves by inserting metal rods in the centrifuge tube that are in direct contact with the sample. This metal rod can reflect the ultrasonic waves generated by the ultrasonic generating device at the bottom of the water tank, and enhance the ultrasonic crushing effect of the sample. However, unlike the conventional probe, the metal rod does not directly generate ultrasonic waves and does not cause corrosion and the like.


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