How to dry materials with high sugar content or heat sensitivity in small spray dryer

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Shanghai Haozhuang specializes in the production of small spray dryers, and has successfully created the small spray dryer brand Haozhuang (LNB)! Haozhuang small spray dryers have a high-quality cast brand! So how does the small spray dryer dry sugar content is relatively high or heat sensitive The following materials are provided by senior engineers from Haozhuang: the problem of difficulty in drying materials containing organic solvents in the spray drying of small spray dryers, general organic solvents will be flammable and explosive. Explosion-proof closed laboratory spray dryers The material can be circulated in a closed drying system. The whole system is filled with inert gas (such as nitrogen or argon), which can avoid the contact between the organic solvent gas and the external oxygen, ensuring safe production. The spray dryer uses a safe nitrogen (or other inert gas) closed circulation method. The entire system is in a closed state. The oxygen concentration is monitored online. Once the oxygen concentration in the system reaches 2%, the system will automatically shut down and alarm. It is a small spray dryer dedicated to laboratory organic solvents with good safety and easy operation. It can process flammable and toxic solvents through the use of nitrogen closed circulation and complete solvent recovery. dry. Moreover, since the boiling point of the organic solvent is low, it is possible to dry materials that are easily thermally denatured by low-temperature drying.

The spray dryer spray-drys the sugar content is relatively high (if juice, Chinese herbal medicine or natural product extract) or heat-sensitive materials (such as enzyme preparation live bacteria, etc.)

Because most polysaccharide disaccharides have a relatively low melting point, the sugar melts when heated, and the polysaccharide disaccharide itself is relatively easy to absorb moisture, so the ordinary spray dryer will easily stick to the wall, not easy Get good dry powder or granules. In addition, like enzyme preparations, live bacteria, and some polymer materials that are more easily denatured at high temperatures, using ordinary spray dryers, the materials are very susceptible to inactivation or denaturation. Temperature, you can get better experimental results.

The advantages of spray dryers are mainly concentrated in the following points:

(1) The drying speed of the spray dryer is very fast. After the material liquid is sprayed, the surface area is large. In high-temperature airflow, it can evaporate instantly.

(2) The temperature of the droplets in the drying process of the spray dryer is not high, and the product quality is good. The temperature range used for spray drying is very wide (80-800 degrees). Even if high-temperature hot air is used, the exhaust temperature will not be very high. In the initial stage of drying, the temperature of the material does not exceed the humidity of the surrounding hot air. it is good. For example, defects such as protein changes, vitamin loss, and oxidation are less likely to occur. The quality of heat-sensitive materials, organisms and drugs can basically be close to the standard of drying under vacuum.

(3) The spray dryer product has good dispersibility, fluidity and solubility. Because the drying process is completed in air, the product can basically maintain a spherical shape similar to droplets, and has good dispersibility, fluidity and Solubility.

(4) The production process of the spray dryer is disintegrated and the operation control is convenient. Spray drying is usually used to process solutions with a moisture content of 40% -60%. Even if the moisture content is as high as 90%, it can also be dried into a powder without concentration. Shaped products. Most products do not need to be crushed and sieved after drying, which reduces the production process and simplifies the production process. The particle size, bulk density and moisture of the product can be adjusted within a certain range by changing the operating conditions, and the control and management are very convenient.

(5) Prevent the occurrence of pollution and improve the production environment. Because spray drying is carried out in a closed drying tower, this prevents the dry products from flying in the workshop. For toxic and odorous materials, the production process of the closed circulation system can be used to burn the toxic and odorous gases to prevent atmospheric pollution and improve the production environment.

(6) The spray dryer is suitable for continuous large-scale production. Spray drying can meet the requirements of industrial large-scale production. After continuous discharge of the dried product, the post-processing can be combined with a cooler and wind power to form a continuous production operation line.

For more information about small spray dryers, please consult Shanghai Haozhuang Instrument Co., Ltd., and look forward to your call!

It is suitable for type 2 diabetes. It is a weekly dipeptidyl peptidase IV (DPP-4) inhibitor. It can control blood sugar levels by selectively and continuously inhibiting DPP-4. DPP-4 is an enzyme that can trigger the inactivation of incretin (glucagon-like peptide-1 (GLP-1) and glucose-dependent insulin-promoting polypeptide (GIP). It plays an important role in regulation. Inhibiting DPP-4 can increase blood glucose level-dependent insulin secretion, thereby controlling blood glucose levels.

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